The Lancet Global Health
 2015
DOI: 10.1016/s2214-109x(15)00151-5
|Get access via publisher |Summarize |Cite
|
Sign up to set email alerts

Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED)

James A Platts-Mills
1
,
Sudhir Babji
2
,
Ladaporn Bodhidatta
3
et al.

Abstract: There was substantial heterogeneity in pathogen-specific burdens of diarrhoea, with important determinants including age, geography, season, rotavirus vaccine usage, and symptoms. These findings suggest that although single-pathogen strategies have an important role in the reduction of the burden of severe diarrhoeal disease, the effect of such interventions on total diarrhoeal incidence at the community level might be limited.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
509
258
179
61

Citation Types

63
854
4
7

Year Published

2000
2000
2026
2026

Publication Types

Select...
750
68
47
31

Relationship

112
784

Authors

Journals

citations

Cited by 884 publications

(928 citation statements)
references

References 38 publications

63
854
4
7
Order By: Relevance
“…This is consistent with our finding that the single water arm had no reduction in infections with chlorine-resistant Giardia is a major cause of diarrhea in Bangladesh. , Cryptosporidium infections (measured at the year two time point) were rare in our study; settings with high Cryptosporidium incidence would be another example where chlorination may reduce indicator bacteria in drinking water but not affect diarrhea. Our E. coli measurements also demonstrate a reduction in fecal exposure through food in the handwashing arm and, coupled with our observation of less dirt on caregiver hands in this arm, suggest reduced caregiver hand contamination.…”
Section: Resultssupporting
confidence: 91%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
“…This is consistent with our finding that the single water arm had no reduction in infections with chlorine-resistant Giardia is a major cause of diarrhea in Bangladesh. , Cryptosporidium infections (measured at the year two time point) were rare in our study; settings with high Cryptosporidium incidence would be another example where chlorination may reduce indicator bacteria in drinking water but not affect diarrhea. Our E. coli measurements also demonstrate a reduction in fecal exposure through food in the handwashing arm and, coupled with our observation of less dirt on caregiver hands in this arm, suggest reduced caregiver hand contamination.…”
Section: Resultssupporting
confidence: 91%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
“…Most of the Shigella qPCR positive samples were detected in children older than 12 months of age (25 out of 37, 69%) ( Fig. 1A ), consistent with the results of previous studies ( 3 , 43 ). In addition, most of the Shigella positive samples (29 out of 37, 81%) were collected between the months of November and April, which coincides with the rainy season in Malawi ( Fig.…”
Section: Resultssupporting
confidence: 91%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
“…Our data are consistent with recent studies 8,29 reporting early and diverse enteropathogen exposure in low-income settings. For example, among nondiarrheal stool samples collected from Bangladeshi infants at 1 month of age, coinfections were highly prevalent (mean: 2.5 enteropathogens per stool).…”
Section: Discussionsupporting
confidence: 93%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
scite logo

Scite is an AI-powered platform that helps researchers discover and evaluate scientific literature through Smart Citations, showing whether studies support or contradict a claim. Now part of Research Solutions, Scite has indexed 1.6B+ citations, partners with 30+ publishers, and serves 2M users worldwide.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Status

Copyright © 2026 Scite LLC. All rights reserved.

Made with 💙 for researchers

Part of the Research Solutions Family.

Research Solutions Logo