2025
The genetics of preimplantation embryonic arrest: the role of aneuploidies
Abstract: Purpose of the review Aneuploidy is a major cause of embryonic arrest. While meiotic aneuploidies, especially maternal, are a well-documented cause of embryo and fetal arrest, increasing evidence highlights the crucial role played by mitotic aneuploidies. This review explores the molecular and cellular pathways underlying these abnormalities, focusing on abnormal cleavage, chromatin cohesion, spindle stability, maternal effect genes, and mitochondria. Recent findin…
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2025
2025
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Cited by 2 publications
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