Patient
 2015
DOI: 10.1007/s40271-015-0145-9
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The Impact of Chronic Urticaria from the Patient’s Perspective: A Survey in Five European Countries

Maria‐Magdalena Balp
1
,
Jeffrey Vietri
2
,
Haijun Tian
3
et al.

Abstract: BackgroundChronic spontaneous urticaria (CSU) is associated with considerable burden, but data from European patients are limited.MethodsThis study is a retrospective, cross-sectional analysis of National Health and Wellness Survey data from the five largest EU countries (5EU: France, Germany, Italy, Spain, and the UK) collected between 2010 and 2013. Burden of disease for patients with CSU was estimated by comparing individuals currently treated for chronic urticaria (proxy CSU cases) with controls selected f… Show more

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Cited by 120 publications

(139 citation statements)
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“…They concerned an anxiety level, which was higher in individuals suffering from urticaria. This result is consistent with other studies presenting enhanced anxiety symptoms in CU patients [ 11 , 13 , 36 – 39 ]. Taking into consideration that almost one third of the CU group reported stress (which is usually experienced as fear [ 40 ]) as a causative factor, we could consider a specific vicious cycle formulation.…”
Section: Discussionsupporting
confidence: 94%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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“…They concerned an anxiety level, which was higher in individuals suffering from urticaria. This result is consistent with other studies presenting enhanced anxiety symptoms in CU patients [ 11 , 13 , 36 – 39 ]. Taking into consideration that almost one third of the CU group reported stress (which is usually experienced as fear [ 40 ]) as a causative factor, we could consider a specific vicious cycle formulation.…”
Section: Discussionsupporting
confidence: 94%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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“…Differences in HRQoL exceeded minimally important differences for MCS and SF-6D score thresholds [ 19 , 25 , 26 ]. In the current study, CU respondents also had higher odds of experiencing anxiety and sleep difficulties than controls, which was consistent with previous research [ 5 , 6 ]. Additionally, CU has been associated with significantly greater odds of any physician visit, an ER visit, or a hospitalization [ 5 ], which are in agreement with results from the present study.…”
Section: Discussionsupporting
confidence: 92%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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“…worse) in the CU patients than the overall PsO patients or mild PsO, but similar to the scores reported by moderate/severe PsO patients. These findings are consistent with the results of previous studies which showed that CU patients have a poorer HRQoL in certain dimensions than patients with PsO6, 10, 17 and atopic dermatitis 17. CU patients report worse scores than PsO patients on mood and physical discomfort in a comparative study published by Grob et al 17.…”
Section: Discussionsupporting
confidence: 92%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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