2020
DOI: 10.1101/2020.01.25.919688
|Get access via publisher |Summarize |Cite
Preprint
|
Sign up to set email alerts

MRCA time and epidemic dynamics of the 2019 novel coronavirus

Chi Zhang
1
,
Mei Wang
2

Abstract: 11The 2019 novel coronavirus (2019-nCoV) have emerged from Wuhan, China. Studying the 12 epidemic dynamics is crucial for further surveillance and control of the outbreak. We employed 13 a Bayesian framework to infer the time-calibrated phylogeny and the epidemic dynamics 14 represented by the effective reproductive number (Re) changing over time from 33 genomic 15 sequences available from GISAID. The time of the most recent common ancestor (MRCA) 16

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
19
11
5
2

Citation Types

7
27
0
0

Year Published

2020
2020
2022
2022

Publication Types

Select...
22
12
1

Relationship

0
35

Authors

Journals

citations

Cited by 35 publications

(34 citation statements)
references

References 16 publications

7
27
0
0
Order By: Relevance
“…For all periods the effective reproduction numbers decrease in time. As new data were reported daily, we followed with subsequent analysis in near-real time with three periods as shown in Table 2 In contrast, a simple linearization of Re in time (Figure 3) back-estimated the original basic reproduction number R0 at about 2.4 to 2.5, agreeing well with other values recently reported Liu et al, 2020;Majumder & Mandl, 2020;Zhang & Wang, 2020a, 2020bZhao et al, 2020a). The discrepancy between these two estimates can be attributed a potential loss of virulence of the virus but most likely due to extreme measures to contain virus spread in China.…”
Section: Resultssupporting
confidence: 80%
“…In contrast, a simple linearization of R e in time (Figure 3 ) back-estimated the original basic reproduction number R 0 at about 2.4 to 2.5, agreeing well with other values recently reported (Imai, Dorigatti, Cori, Riley, & Ferguson, 2020; Liu et al, 2020; Majumder & Mandl, 2020; Zhang & Wang, 2020a, 2020b; Zhao et al, 2020a). The discrepancy between these two estimates can be attributed a potential loss of virulence of the virus but most likely due to extreme measures to contain virus spread in China.…”
Section: Introductionsupporting
confidence: 90%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
“…For all periods the effective reproduction numbers decrease in time. As new data were reported daily, we followed with subsequent analysis in near-real time with three periods as shown in Table 2 In contrast, a simple linearization of Re in time (Figure 3) back-estimated the original basic reproduction number R0 at about 2.4 to 2.5, agreeing well with other values recently reported Liu et al, 2020;Majumder & Mandl, 2020;Zhang & Wang, 2020a, 2020bZhao et al, 2020a). The discrepancy between these two estimates can be attributed a potential loss of virulence of the virus but most likely due to extreme measures to contain virus spread in China.…”
Section: Resultssupporting
confidence: 80%
“…In contrast, a simple linearization of R e in time (Figure 3 ) back-estimated the original basic reproduction number R 0 at about 2.4 to 2.5, agreeing well with other values recently reported (Imai, Dorigatti, Cori, Riley, & Ferguson, 2020; Liu et al, 2020; Majumder & Mandl, 2020; Zhang & Wang, 2020a, 2020b; Zhao et al, 2020a). The discrepancy between these two estimates can be attributed a potential loss of virulence of the virus but most likely due to extreme measures to contain virus spread in China.…”
Section: Introductionsupporting
confidence: 90%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
“…The probability that an exposed person turns into a confirmed infected patient (δ) was 0.079, which is similar to the reported literature [28]. The removal rate (γ ) was 0.001, and is consistent with the reported literature [17]. The death rate (γ 0 ) was 0.0009.…”
Section: Parameters Estimation and Forecastsupporting
confidence: 88%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
“…The probability that an exposed person turns into a confirmed infected patient ( ) is 0.079, which is similar to the reported literature [21]. The removal rate ( ) is 0.001, and is consistent with the reported literature [14]. ; ; .…”
Section: Parameters Estimation and Forecastsupporting
confidence: 87%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
scite logo

Scite is an AI-powered platform that helps researchers discover and evaluate scientific literature through Smart Citations, showing whether studies support or contradict a claim. Now part of Research Solutions, Scite has indexed 1.6B+ citations, partners with 30+ publishers, and serves 2M users worldwide.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Status

Copyright © 2026 Scite LLC. All rights reserved.

Made with 💙 for researchers

Part of the Research Solutions Family.

Research Solutions Logo