Motility-Driven Glass and Jamming Transitions in Biological Tissues

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Mège

³

et al. 2025

Preprint

0

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…For systems exhibiting cage effects, the TMSD shows a pronounced plateau at intermediate times, reflecting transient confinement that persists over a broad range of time scales ( 13, 28, 29 ). However, unlike the predictions of some vertex and Voronoi models ( 16-22 ), our data does not show such a plateau. To eliminate the possible influence of local collective cell migration related to Mermin-Wagner fluctuations, we have calculated the “cage related TMSD”, Fig.…”

Section: Resultscontrasting

confidence: 99%

The complex microscopic dynamics of cells in high-density epithelial tissues

Shen

¹

,

²

,

Mège

³

et al. 2025

Preprint

0

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…9(f) . Consistent with prior research findings [ 7 , 8 ], we have observed that a jammed state can be transitioned to an unjammed state by elevating cell motility. Furthermore, we also find the reinforcement of cell-cell adhesion will suppress unjamming, which is supported by experiments [ 14 , 58 ].…”

Section: Model Resultssupporting

confidence: 93%

Confinement, Jamming, and Adhesion in Cancer Cells Dissociating from a Collectively Invading Strand

¹

,

Law

²

,

Ipiña

³

et al. 2025

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…9(f). Consistent with prior research findings [7, 8], we have observed that a jammed state can be transitioned to an unjammed state by elevating cell motility. Furthermore, we also find the reinforcement of cell-cell adhesion will suppress unjamming, which is supported by experiments [14, 52].…”

Section: Model Resultssupporting

confidence: 93%

Confinement, jamming, and adhesion in cancer cells dissociating from a collectively invading strand

¹

,

Law

²

,

Ipiña

³

et al. 2024

Preprint

0

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.