2006
DOI: 10.1037/0882-7974.21.1.140
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Loneliness as a specific risk factor for depressive symptoms: Cross-sectional and longitudinal analyses.

Abstract: The extent to which loneliness is a unique risk factor for depressive symptoms was determined in 2 population-based studies of middle-aged to older adults, and the possible causal influences between loneliness and depressive symptoms were examined longitudinally in the 2nd study. In Study 1, a nationally representative sample of persons aged 54 and older completed a telephone interview as part of a study of health and aging. Higher levels of loneliness were associated with more depressive symptoms, net of the … Show more

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Cited by 2,219 publications

(1,772 citation statements)
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“…Indeed, Bookwala and Franks (2005) found negative marital quality exacerbated feelings of depression among functionally limited older adults, while positive marital quality had no moderating effect. Rather than our findings contradicting Bookwala and Franks’s, however, the absence of any moderating effect of negative marital quality on loneliness may reflect that loneliness and depressive symptoms arise from different underlying processes (Cacioppo et al 2006), or it may be that negative marital quality is less consequential for loneliness among disabled older adults.…”
Section: Discussioncontrasting
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Indeed, Bookwala and Franks (2005) found negative marital quality exacerbated feelings of depression among functionally limited older adults, while positive marital quality had no moderating effect. Rather than our findings contradicting Bookwala and Franks’s, however, the absence of any moderating effect of negative marital quality on loneliness may reflect that loneliness and depressive symptoms arise from different underlying processes (Cacioppo et al 2006), or it may be that negative marital quality is less consequential for loneliness among disabled older adults.…”
Section: Discussioncontrasting
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…These results deserve attention for a couple of reasons. The strong relationship between perceived isolation and mental health is in line with previous research suggesting that loneliness is particularly deleterious for mental health (Cacioppo et al 2006; Heikkinen and Kauppinen 2004). An increase of one standard deviation on the perceived isolation scale is associated with about a one-half reduction in the odds of having better mental health (e −.755 = .470).…”
Section: Resultssupporting
confidence: 89%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Our results confirm the findings of multiple empirical studies which emphasize the pivotal role of loneliness for the causation of depression (Adams, Sanders, & Auth, 2004;Alpass & Neville, 2003;Cacioppo et al, 2010;Cacioppo et al, 2006b;Golden et al, 2009;Green et al, 1992;Heikkinen & Kauppinen, 2004;Luanaigh & Lawlor, 2008;Prince, Harwood, Blizard, Thomas, & Mann, 1997;Russell, Cutrona, Rose, & Yurko, 1984;Stek et al, 2005;Tiikkainen & Heikkinen, 2005).…”
Section: Discussionsupporting
confidence: 94%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.