Ophthalmology
 2013
DOI: 10.1016/j.ophtha.2012.09.055
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Enhanced Detection of Open-angle Glaucoma with an Anatomically Accurate Optical Coherence Tomography–Derived Neuroretinal Rim Parameter

Balwantray C. Chauhan
1
,
Neil O’Leary
2
,
Faisal A. Almobarak
3
et al.

Abstract: Objective Neuroretinal rim assessment based on the clinical optic disc margin (DM) lacks a sound anatomic basis for 2 reasons: (1) The DM is not reliable as the outer border of rim tissue because of clinically and photographically invisible extensions of Bruch’s membrane (BM) inside the DM and (2) nonaccountability of rim tissue orientation in the optic nerve head (ONH). The BM opening-minimum rim width (BMO-MRW) is a parameter that quantifies the rim from its true anatomic outer border, BMO, and accounts for … Show more

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Cited by 373 publications

(403 citation statements)
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“…Regarding the AUCs for discriminating early glaucoma from glaucoma suspect, the BMO-MRW showed generally higher diagnostic performance than pRNFL thickness. Our findings are consistent with those of previous studies 27,52. Chauhan et al27 reported a higher glaucoma diagnostic performance of BMO-MRW than that of pRNFL thickness in all regions except for the superonasal side as well as the overall average value.…”
Section: Discussionsupporting
confidence: 94%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
“…Regarding the AUCs for discriminating early glaucoma from glaucoma suspect, the BMO-MRW showed generally higher diagnostic performance than pRNFL thickness. Our findings are consistent with those of previous studies 27,52. Chauhan et al27 reported a higher glaucoma diagnostic performance of BMO-MRW than that of pRNFL thickness in all regions except for the superonasal side as well as the overall average value.…”
Section: Discussionsupporting
confidence: 94%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
“…We found lower values in RNFL thickness measurements even using APS in the global and sectorial analysis of moderately myopic individuals compared with low/no myopia; these were significantly lower in the global and Nasal Superior (NS) sector. This agrees with those studies that show that myopic individuals show a thinner RNFL layer when studied with SD-OCT (18-21). Due to this, healthy myopic subjects are frequently classified as abnormal when compared with the normative database.…”
Section: Discussionsupporting
confidence: 93%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
“……”
Section: Discussionsupporting
confidence: 92%
“……”
Section: Discussionsupporting
confidence: 92%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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