Clinical Characteristics, Management, and Outcomes of Patients Diagnosed With Acute Pulmonary Embolism in the Emergency Department

Pollack, Charles V.; Schreiber, Donald; Goldhaber, Samuel Z.; Slattery, David; Fanikos, John; O’Neil, Brian J.; Thompson, James; Hiestand, Brian; Briese, Beau; Pendleton, Robert C.; Miller, Chadwick D.; Kline, Jeffrey A.

doi:10.1016/j.jacc.2010.05.071

Journal of the American College of Cardiology

2011

DOI: 10.1016/j.jacc.2010.05.071

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Clinical Characteristics, Management, and Outcomes of Patients Diagnosed With Acute Pulmonary Embolism in the Emergency Department

Charles V. Pollack

¹

,

Donald Schreiber

²

,

Samuel Z. Goldhaber

³

et al.

Abstract: Patients diagnosed with acute PE in U.S. EDs have high functional status, and their mortality rate is low. These registry data suggest that appropriate initial medical management of ED patients with severe PE with anticoagulation is poorly standardized and indicate a need for research to determine the appropriate threshold for empiric treatment when PE is suspected before diagnostic confirmation.

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Cited by 544 publications

(413 citation statements)

References 26 publications

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26

Mentioning

332

Contrasting

9

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“…The cluster analysis based on the original version is the most appropriate way to use this tool in this setting. Although the overall 30-day mortality rate after acute PE observed in our sample is high when compared with that reported in international studies, 6 , 9 , 10 ) it is in agreement with data from a study on this topic conducted in Brazil 7 . It is necessary that prospective multicenter studies be conducted in Brazil, in order to further assess mortality associated with acute PE in our population.…”

Section: Discussionsupporting

confidence: 92%

Validation of the Pulmonary Embolism Severity Index for risk stratification after acute pulmonary embolism in a cohort of patients in Brazil

Soriano

¹

,

Castro

²

,

Vilalva

³

et al. 2019

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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“…The cluster analysis based on the original version is the most appropriate way to use this tool in this setting. Although the overall 30-day mortality rate after acute PE observed in our sample is high when compared with that reported in international studies, 6 , 9 , 10 ) it is in agreement with data from a study on this topic conducted in Brazil 7 . It is necessary that prospective multicenter studies be conducted in Brazil, in order to further assess mortality associated with acute PE in our population.…”

Section: Discussionsupporting

confidence: 92%

Validation of the Pulmonary Embolism Severity Index for risk stratification after acute pulmonary embolism in a cohort of patients in Brazil

Soriano

¹

,

Castro

²

,

Vilalva

³

et al. 2019

Get access via publisher Add to dashboard Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

show abstract

“…Since mortality in patients diagnosed with PE was infrequent, we were unable to generate robust confidence intervals for these characteristics or assess for trends. We can, however, confidently conclude that in-hospital mortality in patients diagnosed with PE in the ED was very low and this agrees with recently reported data [ 10 ]. Finally, it is possible that the changing demographics of the US population could account for the increase in proportion of ED visits with a diagnosis of PE.…”

Section: Discussionsupporting

confidence: 93%

National trends in emergency room diagnosis of pulmonary embolism, 2001–2010: a cross-sectional study

Schissler

¹

,

Rozenshtein

²

,

Schluger

³

et al. 2015

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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“…The thromboembolic risk factors reported in our series were similar to those found in other scientific reviews. In agreement with previous studies, a sedentary lifestyle, obesity, and cancer were the most important thromboembolic risk factors associated with right heart thrombi [9]. Hypertension was the most frequent comorbidity in our series, but was not significantly associated with right heart thrombi.…”

Section: Discussionsupporting

confidence: 92%

A Prospective Cross‐Sectional Cohort Study on Factors Associations With Right Heart Thrombi and Pulmonary Embolism

Nacanabo¹,

Seghda²,

Dah³

et al. 2025

Health Science Reports

0

Get access via publisher Add to dashboard Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

show abstract

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