Rheumatol Int
 2023
DOI: 10.1007/s00296-023-05275-9
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Central and peripheral mechanisms of pain in fibromyalgia: scoping review protocol

Iván Pérez‐Neri
1
,
Hugo Sandoval
2
,
M. Dulce Estêvão
3
et al.
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Cited by 17 publications

(4 citation statements)
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“…Together, our findings highlight the complex and multifactorial effects of fibromyalgia microbiota across several systems in mice. Similarly, humans with fibromyalgia exhibit a wide range of phenotypes, including the sensitization of the peripheral and central nervous systems 20,21 , immune dysregulation [22][23][24] , and metabolomic alterations 3,[25][26][27][28][29] . Notably, individuals with fibromyalgia often experience functional gastrointestinal disorders, including irritable bowel syndrome (IBS) and functional dyspepsia 30,31 .…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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“…Together, our findings highlight the complex and multifactorial effects of fibromyalgia microbiota across several systems in mice. Similarly, humans with fibromyalgia exhibit a wide range of phenotypes, including the sensitization of the peripheral and central nervous systems 20,21 , immune dysregulation [22][23][24] , and metabolomic alterations 3,[25][26][27][28][29] . Notably, individuals with fibromyalgia often experience functional gastrointestinal disorders, including irritable bowel syndrome (IBS) and functional dyspepsia 30,31 .…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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“……”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…FM is a controversial issue because of the lack of specific biological and instrumental biomarkers and comorbidity with several other disorders [88]. The diagnosis of FM is challenging, because the symptoms may resemble those of other pain conditions such as Raynaud and Sjögren syndromes [89]. The mechanism underlying FM is obscure, but it is believed that central sensitization is an important factor [90].…”
Section: Fibromyalgiamentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
show abstract
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