Brain development and aging: Overlapping and unique patterns of change

Tamnes, Christian K.; Walhovd, Kristine B.; Dale, Anders M.; Østby, Ylva; Grydeland, Håkon; Richardson, George B.; Westlye, Lars T.; Roddey, J. Cooper; Hagler, Donald J.; Due‐Tønnessen, Paulina; Holland, Dominic; Fjell, Anders M.

doi:10.1016/j.neuroimage.2012.11.039

NeuroImage

2013

DOI: 10.1016/j.neuroimage.2012.11.039

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Brain development and aging: Overlapping and unique patterns of change

Christian K. Tamnes

¹

,

Kristine B. Walhovd

²

,

Anders M. Dale

³

et al.

Abstract: Early-life development is characterized by dramatic changes, impacting lifespan function more than changes inany other period. Developmental origins of neurocognitive late-life functions are acknowledged, but detailed longitudinal magnetic resonance imaging studies of brain maturation and direct comparisons with aging are lacking. To these aims, a novel method was used to measure longitudinal volume changes in development (n = 85, 8–22 years) and aging (n = 142, 60–91 years). Developmental reductions exceeded … Show more

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Cited by 301 publications

(305 citation statements)

References 97 publications

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27

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271

Contrasting

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“…This region displayed the highest gray matter volume in late childhood and early adolescence, and showed consistent decreases in gray matter volume (1.2-1.7% per year) across the teen years before decelerating in the early twenties. This finding is consistent with findings from other longitudinal samples, which have shown decreasing gray matter volume in the PFC between late childhood and early adulthood [5,29]. Comparing all three ROIs at a group level, these data lend support to a structural mismatch in developmental timing between the amygdala and the PFC, but do not provide evidence of a clear structural mismatch between the NAcc and the PFC during adolescence, since both regions continue to show volume change into early adulthood.…”

Section: Discussionsupporting

confidence: 93%

“…For the NAcc, the best fitting group model displayed a linear decrease in volume throughout the studied age range (8-25 years). This result is similar to that found in previous longitudinal studies of NAcc structural development [5,6], which also reported linear decreases in adolescence, although there have been contrasting results [7,8]. Taken together, the current report and previous studies suggest that, at a group level, the NAcc decreases in volume between adolescence and adulthood, whereas it is likely that the amygdala increases in late childhood and early adolescence before stabilizing in volume by mid-to-late adolescence, with significant interindividual variability in the development of both regions.…”

Section: Discussionsupporting

confidence: 93%

See 1 more Smart Citation

The Developmental Mismatch in Structural Brain Maturation during Adolescence

Mills

¹

,

Goddings

²

,

Clasen

³

et al. 2014

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

show abstract

“…This region displayed the highest gray matter volume in late childhood and early adolescence, and showed consistent decreases in gray matter volume (1.2-1.7% per year) across the teen years before decelerating in the early twenties. This finding is consistent with findings from other longitudinal samples, which have shown decreasing gray matter volume in the PFC between late childhood and early adulthood [5,29]. Comparing all three ROIs at a group level, these data lend support to a structural mismatch in developmental timing between the amygdala and the PFC, but do not provide evidence of a clear structural mismatch between the NAcc and the PFC during adolescence, since both regions continue to show volume change into early adulthood.…”

Section: Discussionsupporting

confidence: 93%

“…For the NAcc, the best fitting group model displayed a linear decrease in volume throughout the studied age range (8-25 years). This result is similar to that found in previous longitudinal studies of NAcc structural development [5,6], which also reported linear decreases in adolescence, although there have been contrasting results [7,8]. Taken together, the current report and previous studies suggest that, at a group level, the NAcc decreases in volume between adolescence and adulthood, whereas it is likely that the amygdala increases in late childhood and early adolescence before stabilizing in volume by mid-to-late adolescence, with significant interindividual variability in the development of both regions.…”

Section: Discussionsupporting

confidence: 93%

The Developmental Mismatch in Structural Brain Maturation during Adolescence

Mills

¹

,

Goddings

²

,

Clasen

³

et al. 2014

Get access via publisher Add to dashboard Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

show abstract

“…We additionally observed that females in earlier phases of puberty showed an earlier peak in caudate volume compared to peers. This supports the notion that puberty, in particular testosterone, may be the driving source behind previously observed inverted-U shaped trajectory in this structure (Tamnes et al, 2013;Lenroot et al, 2007;Wierenga et al, 2014). These results are in line with findings of Herting et al (2014), who showed an interaction effect of age by puberty (Tanner stage and testosterone).…”

Section: Discussionsupporting

confidence: 92%

Unraveling age, puberty and testosterone effects on subcortical brain development across adolescence

Wierenga

¹

,

Bos

²

,

Schreuders

³

et al. 2018

Psychoneuroendocrinology

Self Cite

Get access via publisher Add to dashboard Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

show abstract

“…Likewise the proportion of subjects undergoing increases, decreases or no change remained consistent across each age bin, in keeping with a linear fit. These longitudinal findings in the nucleus accumbens also match the linear fit in our cross‐sectional sample, as well as in previous longitudinal samples finding linear decreases of volume across similar age ranges [Goddings et al, ; Tamnes et al, ; Wierenga et al, ].…”

Section: Discussionsupporting

confidence: 91%

Evolution of deep gray matter volume across the human lifespan

Narvacan

¹

,

Treit

²

,

Camicioli

³

et al. 2017

Human Brain Mapping

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

show abstract

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