Aging Is Associated With Decreased Lactobacillus and Increased Cervicovaginal Inflammation in Canadian Women

Abstract: ProblemAging is characterized by a general dysregulation of systemic immune responses that increases susceptibility to infections and malignancies. Immune cells in the female genital tract (FGT) are regulated by sex hormones, but little is known about the impact of aging and menopause on immunology in the FGT.Method of StudyThis study conducted an age‐focused sub‐analysis of cervicovaginal samples collected from 47 women enrolled in the Vaginal Mucosal Systems study in Winnipeg, Canada. Paired cervicovaginal l… Show more