Age-enhancing cognitive ability shows similar attenuation in task evoked brain networks with aging and preclinical AD

Abstract: Brain aging - with and without pre-clinical Alzheimer’s disease (AD) pathology - are associated with deterioration in the brain networks’ coherence and/or co-activation/deactivation as well as with decline in most cognitive abilities, paving the road for a network-based conceptualization of the brain normal versus pathological aging. However, certain cognitive abilities, like crystallized memory, improve with age, which complicates the explanation of these changes solely through age-related decline in the brai… Show more